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Tobacco is an agricultural product processed from the fresh leaves of plants in the genus Nicotiana. Its most common use is for smoking (tobacco smoking) in the form of a cigarette or cigar. Even in the 26th Century, Tobacco is still an important commercial commodity, used in cigars, cigarettes, and the fillings of pipes. Tobacco is commercially available almost everywhere in dried, cured, and natural forms. Harvest is a producer of tobacco. It also produces other crops with the help of Jotun Heavy Industries. They supply the machines that are crucial to the harvesting of the planet.
- Captain Jacob Keyes was an avid pipe smoker, always keeping a pipe on him.
- Sergeant Johnson smoked Sweet William Cigars.
- The Minister of Fortitude once smoked Hookah tobacco to increase his mental faculties during a meeting.
- Captain Ponder smoked Sweet William Cigars throughout Contact Harvest.
- CPO Mendez smoked Sweet William Cigars, mentioned in Halo: The Fall of Reach.
- Colonel Watts smoked Sweet William Cigars, which lead to his demise when John-117 and his handpicked team of Spartan IIs used the cigars to find him.
- Sergeant Laura "Smoke" Tanner was known to chew tobacco gum, which earned her the nickname "Smoke."